Reduced gastric acid output in cirrhosis: Quantitation and relationships

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Reduced Gastric Acid Output in Cirrhosis: Quantitation and Relationships.

EDITORIAL SYNOPSIS Basal and maximal (post-histamine) acid outputs were significantly reduced in patients with cirrhosis. A subnormal secretory response to stimulation with peptone was also found. Gastric hyposecretion was not related to the aetiology or severity of the hepatic disease nor to the extent or presence of a portal-collateral circulation. Increased gastric production of ammonia in c...

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Determination of Gastric Acid Output

The concentrations of immunoreactive gastrin in serum from portal and peripheral venous blood were determined in 10 patients with indwelling portal catheters before and after feeding. No significant differences were found between the gastrin concentrations in portal and peripheral serum. Gel filtration studies of serum did not reveal any differences between the gastrin components of portal and ...

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The Effects of Cholestasis and Cirrhosis on Gastric Acid and Pepsin Secretions in Rat: Involvement of Nitric Oxide

Objective(s) The liver has major role in the organism homeostasis, interactions with other systems, synthesis and metabolism of bile production, drug detoxification and hormone inactivation. Cholestasis can be defined as an impairment of the bile flow which can lead to hepatocytes necrosis and finally cirrhosis. Some studies reported a gastric acid secretion reduction in cirrhotic subjects, wh...

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Lysosomal Acid Lipase Activity Is Reduced Both in Cryptogenic Cirrhosis and in Cirrhosis of Known Etiology

CONCLUSION Liver cirrhosis is characterized by a severe acquired reduction of LAL-activity, the precise causes and consequences of which need to be further addressed. DBS-determined lysosomal enzyme activities seem to be affected by white blood cell and platelet counts, and the specificity of these tests can be reduced when applied to determined populations, such as cirrhotics.

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The Inhibitory Effect of Ziziphora clinopodioides Lam. on Gastric Acid Output at Basal, Vagotomized and Vagal Stimulated Conditions in Rat

Objective(s) Ziziphora clinopodioides Lam. is a plant widely used in Iranian traditional medicine for gastrointestinal disorders. Several reports have demonstrated antibacterial (Helicobacteria pylori), antioxidant and anti‌inflammatory properties of Z. clinopodioides. The aim of this study was to investigate the effects of aqueous- ethanol extract of Z. clinopodioides on rat’s gastric acid ou...

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ژورنال

عنوان ژورنال: Gut

سال: 1964

ISSN: 0017-5749

DOI: 10.1136/gut.5.5.422